Dr. Ghavami received her M.Sc. from Shiraz University in Iran under the supervision of Prof. Habib Firouzabadi and Prof. Nasser Iranpoor during which she investigated the modified synthesis and characterization of a novel Pd nano-particle catalyst, and studied its application in C-C bond forming reactions. She moved to the United States in 2012 to persue her Ph.D. at Virginia Polytechnic Institute and State University where she joined Prof. Paul R. Carlier’s lab. During the course of her Ph.D., she spent one year as a Medicinal Chemist Co-op at GlaxoSmithKline (GSK). Her graduate research in the laboratory of Prof. Carlier focused on design, synthesis and evaluation of antimalarial compounds. She joined Prof. Hergenrother’s lab in August 2018.


Biological studies and target-engagement of the 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD)-targeting antimalarial agent (1R,3S)-MMV008138 and analogs

Ghavami, M.; Merino, E. F.; Yao, Z.-K.; Elahi, R.; Simpson, M. E.; Fernández-Murga, M. L.; Butler, J. H.; Casasanta, M. A.; Krai, P. M.; Totrov, M. M.; Slade, D. J.; Carlier, P. R.; Cassera, M. B.

ACS Infect. Dis. 20184, 549-559.


Parallel inhibition of amino acid efflux and parasite growth of erythrocytic Plasmodium falciparum by mefloquine and open-ring analogs: implication for the mechanism of antimalarial action

Ghavami, M.; Dapper, C. H.; Dalal, S.; Holzschneider, K.; Klemba, M.; Carlier, P. R.

Biorg. Med. Chem. Lett. 201626, 4846-4850.


Novel isoxazol-3-yl carboxamides and carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae 

Verma, A.; Wong, D. M.; Islam, R.; Tong, F.; Ghavami, M.; Mutunga, J. M.; Slebodnick, C.; Li, J.; Viayna, E.; Lam, P. C.-H.

Biorg. Med. Chem. 201523, 1321-1340.


Cerium (IV) oxide as a neutral catalyst for aldehyde-induced decarboxylative coupling of L-proline with triethylphosphite and nitromethane

Firouzabadi, H.; Iranpoor, N.; Ghaderi, A.; Ghavami, M.

Tetrahedron Lett. 201253, 5515-5518.

Palladium nano-particles supported on aminopropyl functionalized clay as efficient catalysts for phosphine-free C-C bond formation via Mizoroki-Heck and Suzuki-Miyaura reactions

Firouzabadi, H.; Iranpoor, N.; Ghaderi, A.; Ghavami, M.; Hoseini, S. J.

Bull. Chem. Soc. Jpn. 201184, 100-109.

Highlighted in Synfacts:

Heck and Suzuki Reactions Using Supported Palladium Nanoparticles

Firouzabadi, H.; Iranpoor, N.; Ghaderi, A.; Ghavami, M.; Hoseini, S.

Synfacts 20112011, 0450-0450.

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